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KMID : 0359720080260010050
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Journal of the Korean Neurological Association
2008 Volume.26 No. 1 p.50 ~ p.54
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A Pathology-proven Case of Schilder’s Disease
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Kim Byung-Su
Kim Byoung-Joon
Lee Kwang-Ho
Kim Gyeong-Moon
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Abstract
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Schilder’s disease or myelinoclastic diffuse sclerosis (MDS) is a rare variant of multiple sclerosis. We report a 66-year-old woman with progressive motor weakness and diffuse white matter degeneration on MRI, which satisfies the Poser’s restrictive criteria of MDS. As previously reported cases of probable Schilder’s disease did not meet the criteria correctly, we consider our patient is the first pathology-proven case of MDS in Korea.
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KEYWORD
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Diffuse sclerosis, Demyelinating disease, White matter
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